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PKM2 regulates chromosome segregation and mitosis progression of tumor cells
Tumor-specific pyruvate kinase M2 (PKM2) is instrumental in both aerobic glycolysis and gene transcription. PKM2 regulates G1-S phase transition by controlling cyclin D1 expression. However, it is not known whether PKM2 directly controls cell cycle progression. We show here that PKM2, but not PKM1,...
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| Hoofdauteurs: | , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3955203/ https://ncbi.nlm.nih.gov/pubmed/24316223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.11.001 |
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