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RNF8 mediates histone H3 ubiquitylation and promotes glycolysis and tumorigenesis
Disassembly of nucleosomes in which genomic DNA is packaged with histone regulates gene expression. However, the mechanisms underlying nucleosome disassembly for gene expression remain elusive. We show here that epidermal growth factor receptor activation results in the binding of the RNF8 forkhead-...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5461008/ https://ncbi.nlm.nih.gov/pubmed/28507061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170015 |
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