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DNA‐induced unfolding of the thyroid hormone receptor α A/B domain through allostery
The A/B domains of nuclear receptors such as thyroid receptor α (TRα) are considered to be conformationally flexible and can potentially adopt multiple structural conformations. We used intrinsic tryptophan fluorescence quenching and circular dichroism spectroscopy to characterize the unfolding of t...
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| Publicado no: | FEBS Open Bio |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458466/ https://ncbi.nlm.nih.gov/pubmed/28593140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12229 |
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