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Probing Allostery Through DNA
Allostery is well documented for proteins but less recognized for DNA-protein interactions. Here we report that specific binding of a protein on DNA is substantially stabilized or destabilized by another protein bound nearby. The ternary complex's free energy oscillates as a function of the sep...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3586787/ https://ncbi.nlm.nih.gov/pubmed/23413354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1229223 |
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