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Allostery through protein-induced DNA bubbles

Allostery through DNA is increasingly recognized as an important modulator of DNA functions. Here, we show that the coalescence of protein-induced DNA bubbles can mediate allosteric interactions that drive protein aggregation. We propose that such allostery may regulate DNA's flexibility and th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Traverso, Joseph J., Manoranjan, Valipuram S., Bishop, A. R., Rasmussen, Kim Ø., Voulgarakis, Nikolaos K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356955/
https://ncbi.nlm.nih.gov/pubmed/25762409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09037
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