Cooperative DNA Recognition Modulated by an Interplay between Protein-Protein Interactions and DNA-Mediated Allostery

Highly specific transcriptional regulation depends on the cooperative association of transcription factors into enhanceosomes. Usually, their DNA-binding cooperativity originates from either direct interactions or DNA-mediated allostery. Here, we performed unbiased molecular simulations followed by...

Full description

Saved in:
Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Merino, Felipe, Bouvier, Benjamin, Cojocaru, Vlad
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465831/
https://ncbi.nlm.nih.gov/pubmed/26067358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004287
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items