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Modulation of allostery by protein intrinsic disorder

Allostery is an intrinsic property of many globular proteins and enzymes that is indispensable for cellular regulatory and feedback mechanisms. Recent theoretical(1) and empirical(2) observations indicate that allostery is also manifest in intrinsically disordered proteins (IDPs), which account for...

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Autors principals: Ferreon, Allan Chris M., Ferreon, Josephine C., Wright, Peter E., Deniz, Ashok A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718496/
https://ncbi.nlm.nih.gov/pubmed/23783631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12294
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