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Transmission of allostery through the lectin domain in selectin-mediated cell adhesion
The selectins are cell adhesion proteins that must resist applied forces to mediate leukocyte tethering and rolling along the endothelium and have 2 conformational states. Selectin–ligand bond dissociation increases only modestly with applied force, and exhibits catch bond behavior in a low-force re...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629216/ https://ncbi.nlm.nih.gov/pubmed/19118202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810620105 |
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