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Structural basis for selectin mechanochemistry
Selectins are adhesion molecules that resist large tensile forces applied by hydrodynamic forces to leukocytes binding to vessel walls. In crystals, the liganded (high-affinity) and unliganded (low-affinity) conformations differ in orientation between their tandem lectin and EGF domains. I examine h...
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2629181/ https://ncbi.nlm.nih.gov/pubmed/19118197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810784105 |
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