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Rolling and transient tethering of leukocytes on antibodies reveal specializations of selectins

Antibodies immobilized on the wall of a flow chamber can support leukocyte rolling in shear flow. IgM mAb to Lewis(x) (CD15) and sialyl Lewis(x) (CD15s), which are carbohydrate antigens related to selectin ligands, plus mAb to CD48 and CD59, could mediate rolling. IgM and IgG mAb to L-selectin (CD62...

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Detalhes bibliográficos
Main Authors: Chen, Shuqi, Alon, Ronen, Fuhlbrigge, Robert C., Springer, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20341/
https://ncbi.nlm.nih.gov/pubmed/9096365
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