Rolling and transient tethering of leukocytes on antibodies reveal specializations of selectins

Antibodies immobilized on the wall of a flow chamber can support leukocyte rolling in shear flow. IgM mAb to Lewis(x) (CD15) and sialyl Lewis(x) (CD15s), which are carbohydrate antigens related to selectin ligands, plus mAb to CD48 and CD59, could mediate rolling. IgM and IgG mAb to L-selectin (CD62...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Chen, Shuqi, Alon, Ronen, Fuhlbrigge, Robert C., Springer, Timothy A.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1997
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20341/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9096365/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.7.3172
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