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DNA‐induced unfolding of the thyroid hormone receptor α A/B domain through allostery

The A/B domains of nuclear receptors such as thyroid receptor α (TRα) are considered to be conformationally flexible and can potentially adopt multiple structural conformations. We used intrinsic tryptophan fluorescence quenching and circular dichroism spectroscopy to characterize the unfolding of t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS Open Bio
Egile Nagusiak: Fernandez, Elias J., Gahlot, Vandna, Rodriguez, Celeste, Amburn, Jacob
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458466/
https://ncbi.nlm.nih.gov/pubmed/28593140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12229
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