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Discriminatory suppression of homologous recombination by p53
Homologous recombination (HR) is used in vertebrate somatic cells for essential, RAD51-dependent, repair of DNA double-strand-breaks (DSBs), but inappropriate HR can cause genome instability. A transcriptional transactivation-independent role for p53 in suppressing HR has been established, but is no...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15601996/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh986 |
| Oznake: |
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