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Discriminatory suppression of homologous recombination by p53
Homologous recombination (HR) is used in vertebrate somatic cells for essential, RAD51-dependent, repair of DNA double-strand-breaks (DSBs), but inappropriate HR can cause genome instability. A transcriptional transactivation-independent role for p53 in suppressing HR has been established, but is no...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545454/ https://ncbi.nlm.nih.gov/pubmed/15601996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh986 |
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