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A role for human homologous recombination factors in suppressing microhomology-mediated end joining
DNA double-strand breaks (DSBs) are toxic lesions, which if improperly repaired can result in cell death or genomic instability. DSB repair is usually facilitated by the classical non-homologous end joining (C-NHEJ), or homologous recombination (HR) pathways. However, a mutagenic alternative NHEJ pa...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4937322/ https://ncbi.nlm.nih.gov/pubmed/27131361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw326 |
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