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Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions
Ku or DNA ligase 4-independent alternative end joining (alt-EJ) repair of DNA double-strand breaks (DSBs) frequently correlates with increased junctional microhomology. However, alt-EJ also produces junctions without microhomology (apparent blunt joins), and the exact role of microhomology in both a...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943611/ https://ncbi.nlm.nih.gov/pubmed/20460465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq379 |
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