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Homology and enzymatic requirements of microhomology-dependent alternative end joining
Nonhomologous DNA end joining (NHEJ) is one of the major double-strand break (DSB) repair pathways in higher eukaryotes. Recently, it has been shown that alternative NHEJ (A-NHEJ) occurs in the absence of classical NHEJ and is implicated in chromosomal translocations leading to cancer. In the presen...
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Publicado no: | Cell Death Dis |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385936/ https://ncbi.nlm.nih.gov/pubmed/25789972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.58 |
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