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Microhomology Selection for Microhomology Mediated End Joining in Saccharomyces cerevisiae

Microhomology-mediated end joining (MMEJ) anneals short, imperfect microhomologies flanking DNA breaks, producing repair products with deletions in a Ku- and RAD52-independent fashion. Puzzlingly, MMEJ preferentially selects certain microhomologies over others, even when multiple microhomologies are...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Lee, Kihoon, Ji, Jae-Hoon, Yoon, Kihoon, Che, Jun, Seol, Ja-Hwan, Lee, Sang Eun, Shim, Eun Yong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523938/
https://ncbi.nlm.nih.gov/pubmed/30965655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10040284
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