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NHEJ Often Uses Microhomology: Implications for Alternative End Joining
Artemis and PALF (also called APLF) appear to be among the primary nucleases involved in NHEJ and responsible for most nucleolytic end processing in NHEJ. About 60% of NHEJ events show an alignment of the DNA ends that uses 1 or 2 bp of microhomology (MH) between the two DNA termini. Thus, MH is a c...
Enregistré dans:
| Publié dans: | DNA Repair (Amst) |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440676/ https://ncbi.nlm.nih.gov/pubmed/24613510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.02.006 |
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