p53 Gene Targeting by Homologous Recombination in Fish ES Cells

BACKGROUND: Gene targeting (GT) provides a powerful tool for the generation of precise genetic alterations in embryonic stem (ES) cells to elucidate gene function and create animal models for human diseases. This technology has, however, been limited to mouse and rat. We have previously established...

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Detalhes bibliográficos
Main Authors: Yan, Yan, Hong, Ni, Chen, Tiansheng, Li, Mingyou, Wang, Tiansu, Guan, Guijun, Qiao, Yongkang, Chen, Songlin, Schartl, Manfred, Li, Chang-Ming, Hong, Yunhan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602087/
https://ncbi.nlm.nih.gov/pubmed/23527183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059400
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