Dnd Is a Critical Specifier of Primordial Germ Cells in the Medaka Fish

Primordial germ cell (PGC) specification occurs early in development. PGC specifiers have been identified in Drosophila, mouse, and human but remained elusive in most animals. Here we identify the RNA-binding protein Dnd as a critical PGC specifier in the medaka fish (Oryzias latipes). Dnd depletion...

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Detalhes bibliográficos
Main Authors: Ni Hong, Mingyou Li, Yongming Yuan, Tiansu Wang, Meisheng Yi, Hongyan Xu, Huaqiang Zeng, Jianxing Song, Yunhan Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016-03-01
Colecção:Stem Cell Reports
Assuntos:
asymmetric segregation: dnd
lineage tracing
primordial germ cell
RNA particle
single-cell culture
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213671116000199
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