Dnd Is a Critical Specifier of Primordial Germ Cells in the Medaka Fish

Primordial germ cell (PGC) specification occurs early in development. PGC specifiers have been identified in Drosophila, mouse, and human but remained elusive in most animals. Here we identify the RNA-binding protein Dnd as a critical PGC specifier in the medaka fish (Oryzias latipes). Dnd depletion...

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Udgivet i:Stem Cell Reports
Main Authors: Hong, Ni, Li, Mingyou, Yuan, Yongming, Wang, Tiansu, Yi, Meisheng, Xu, Hongyan, Zeng, Huaqiang, Song, Jianxing, Hong, Yunhan
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788760/
https://ncbi.nlm.nih.gov/pubmed/26852942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.01.002
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