p53 Gene Targeting by Homologous Recombination in Fish ES Cells

BACKGROUND: Gene targeting (GT) provides a powerful tool for the generation of precise genetic alterations in embryonic stem (ES) cells to elucidate gene function and create animal models for human diseases. This technology has, however, been limited to mouse and rat. We have previously established...

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Bibliografiske detaljer
Main Authors: Yan, Yan, Hong, Ni, Chen, Tiansheng, Li, Mingyou, Wang, Tiansu, Guan, Guijun, Qiao, Yongkang, Chen, Songlin, Schartl, Manfred, Li, Chang-Ming, Hong, Yunhan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602087/
https://ncbi.nlm.nih.gov/pubmed/23527183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059400
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