p53 Gene Targeting by Homologous Recombination in Fish ES Cells

BACKGROUND: Gene targeting (GT) provides a powerful tool for the generation of precise genetic alterations in embryonic stem (ES) cells to elucidate gene function and create animal models for human diseases. This technology has, however, been limited to mouse and rat. We have previously established...

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Main Authors: Yan, Yan, Hong, Ni, Chen, Tiansheng, Li, Mingyou, Wang, Tiansu, Guan, Guijun, Qiao, Yongkang, Chen, Songlin, Schartl, Manfred, Li, Chang-Ming, Hong, Yunhan
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602087/
https://ncbi.nlm.nih.gov/pubmed/23527183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059400
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