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Efficient p53 gene targeting by homologous recombination in rat‐induced pluripotent stem cells

OBJECTIVES: To generate rat induced pluripotent stem cells (iPSCs) using the PiggyBac (PB) transposon system, and to explore whether these iPSCs would be amenable to genetic manipulation. MATERIALS AND METHODS: The PB transposon system was used to reprogramme rat embryonic fibroblasts (EF) to become...

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Bibliografiske detaljer
Udgivet i:Cell Prolif
Main Authors: Li, G., Chunxu, Y., Guisheng, L.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495543/
https://ncbi.nlm.nih.gov/pubmed/23278941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12000
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