Caricamento...
Inhibition of colony-stimulating factor 1 receptor early in disease ameliorates motor deficits in SCA1 mice
BACKGROUND: Polyglutamine (polyQ) expansion in the protein Ataxin-1 (ATXN1) causes spinocerebellar ataxia type 1 (SCA1), a fatal dominantly inherited neurodegenerative disease characterized by motor deficits, cerebellar neurodegeneration, and gliosis. Currently, there are no treatments available to...
Salvato in:
| Pubblicato in: | J Neuroinflammation |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2017
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5445366/ https://ncbi.nlm.nih.gov/pubmed/28545543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0880-z |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|