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Inhibition of NF-κB signaling in IKKβ(F/F);LysM Cre mice causes motor deficits but does not alter pathogenesis of Spinocerebellar ataxia type 1
Spinocerebellar Ataxia type 1 (SCA1) is a fatal neurodegenerative genetic disease that is characterized by pronounced neuronal loss and gliosis in the cerebellum. We have previously demonstrated microglial activation, measured as an increase in microglial density in cerebellar cortex and an increase...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6033432/ https://ncbi.nlm.nih.gov/pubmed/29975753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200013 |
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