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Mood alterations in mouse models of Spinocerebellar Ataxia type 1

Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by abnormal expansion of glutamine-encoding CAG repeats in the Ataxin-1 (ATXN1) gene. SCA1 is characterized by progressive motor deficits, cognitive decline, and mood changes including anxiety and depression, with longe...

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Publicat a:Sci Rep
Autors principals: Asher, Melissa, Rosa, Juao-Guilherme, Cvetanovic, Marija
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803946/
https://ncbi.nlm.nih.gov/pubmed/33436887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80664-9
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