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LANP mediates neuritic pathology in Spinocerebellar ataxia type 1

Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disease that results from a pathogenic glutamine-repeat expansion in the protein ataxin-1 (ATXN1). Although the functions of ATXN1 are still largely unknown, there is evidence to suggest that ATXN1 plays a role in regula...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cvetanovic, Marija, Kular, Rupinder K., Opal, Puneet
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987943/
https://ncbi.nlm.nih.gov/pubmed/22884877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.07.024
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