Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of β-ENaC in a Human Alveolar Epithelial Cell Line

Acute lung injury is associated with formation of pulmonary edema leading to impaired gas exchange. Patients with acute respiratory distress syndrome (ARDS) require mechanical ventilation to improve oxygenation; however, the use of relatively low tidal volumes (to minimize further injury of the lung...

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發表在:Front Immunol
Main Authors: Gwoździńska, Paulina, Buchbinder, Benno A., Mayer, Konstantin, Herold, Susanne, Morty, Rory E., Seeger, Werner, Vadász, István
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440515/
https://ncbi.nlm.nih.gov/pubmed/28588583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00591
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