Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of β-ENaC in a Human Alveolar Epithelial Cell Line

Acute lung injury is associated with formation of pulmonary edema leading to impaired gas exchange. Patients with acute respiratory distress syndrome (ARDS) require mechanical ventilation to improve oxygenation; however, the use of relatively low tidal volumes (to minimize further injury of the lung...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Gwoździńska, Paulina, Buchbinder, Benno A., Mayer, Konstantin, Herold, Susanne, Morty, Rory E., Seeger, Werner, Vadász, István
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440515/
https://ncbi.nlm.nih.gov/pubmed/28588583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00591
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