The CFTR and ENaC debate: how important is ENaC in CF lung disease?

Cystic fibrosis (CF) is caused by the loss of the cystic fibrosis transmembrane conductance regulator (CFTR) function and results in a respiratory phenotype that is characterized by dehydrated mucus and bacterial infections that affect CF patients throughout their lives. Much of the morbidity and mo...

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Bibliographic Details
Main Authors: Collawn, James F., Lazrak, Ahmed, Bebok, Zsuzsa, Matalon, Sadis
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
Subjects:
Perspectives
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379041/
https://ncbi.nlm.nih.gov/pubmed/22492740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00036.2012
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