Hypercapnia Impairs Na,K-ATPase Function by Inducing Endoplasmic Reticulum Retention of the β-Subunit of the Enzyme in Alveolar Epithelial Cells

Alveolar edema, impaired alveolar fluid clearance, and elevated CO(2) levels (hypercapnia) are hallmarks of the acute respiratory distress syndrome (ARDS). This study investigated how hypercapnia affects maturation of the Na,K-ATPase (NKA), a key membrane transporter, and a cell adhesion molecule in...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Kryvenko, Vitalii, Wessendorf, Miriam, Morty, Rory E., Herold, Susanne, Seeger, Werner, Vagin, Olga, Dada, Laura A., Sznajder, Jacob I., Vadász, István
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7073107/
https://ncbi.nlm.nih.gov/pubmed/32098115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041467
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