TRAF2 Is a Novel Ubiquitin E3 Ligase for the Na,K-ATPase β-Subunit That Drives Alveolar Epithelial Dysfunction in Hypercapnia

Several acute and chronic lung diseases are associated with alveolar hypoventilation leading to accumulation of CO(2) (hypercapnia). The β-subunit of the Na,K-ATPase plays a pivotal role in maintaining epithelial integrity by functioning as a cell adhesion molecule and regulating cell surface stabil...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Gabrielli, Nieves M., Mazzocchi, Luciana C., Kryvenko, Vitalii, Tello, Khodr, Herold, Susanne, Morty, Rory E., Grimminger, Friedrich, Dada, Laura A., Seeger, Werner, Sznajder, Jacob I., Vadász, István
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8283768/
https://ncbi.nlm.nih.gov/pubmed/34277634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.689983
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