TGF-β inhibits alveolar protein transport by promoting shedding, regulated intramembrane proteolysis, and transcriptional downregulation of megalin

Disruption of the alveolar-capillary barrier is a hallmark of acute respiratory distress syndrome (ARDS) that leads to the accumulation of protein-rich edema in the alveolar space, often resulting in comparable protein concentrations in alveolar edema and plasma and causing deleterious remodeling. P...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Lung Cell Mol Physiol
Egile Nagusiak: Mazzocchi, Luciana C., Vohwinkel, Christine U., Mayer, Konstantin, Herold, Susanne, Morty, Rory E., Seeger, Werner, Vadász, István
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6148198/
https://ncbi.nlm.nih.gov/pubmed/28705909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00569.2016
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