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Restoration of Megalin-Mediated Clearance of Alveolar Protein as a Novel Therapeutic Approach for Acute Lung Injury

Acute respiratory distress syndrome constitutes a significant disease burden with regard to both morbidity and mortality. Current therapies are mostly supportive and do not address the underlying pathophysiologic mechanisms. Removal of protein-rich alveolar edema—a clinical hallmark of acute respira...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Vohwinkel, Christine U., Buchäckert, Yasmin, Al-Tamari, Hamza M., Mazzocchi, Luciana C., Eltzschig, Holger K., Mayer, Konstantin, Morty, Rory E., Herold, Susanne, Seeger, Werner, Pullamsetti, Soni S., Vadász, István
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800889/
https://ncbi.nlm.nih.gov/pubmed/28678521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0358OC
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