Megalin mediates transepithelial albumin clearance from the alveolar space of intact rabbit lungs

The alveolo-capillary barrier is effectively impermeable to large solutes such as proteins. A hallmark of acute lung injury/acute respiratory distress syndrome is the accumulation of protein-rich oedema fluid in the distal airspaces. Excess protein must be cleared from the alveolar space for recover...

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Main Authors: Buchäckert, Yasmin, Rummel, Sebastian, Vohwinkel, Christine U, Gabrielli, Nieves M, Grzesik, Benno A, Mayer, Konstantin, Herold, Susanne, Morty, Rory E, Seeger, Werner, Vadász, István
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2012
Teme:
Respiratory
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497570/
https://ncbi.nlm.nih.gov/pubmed/22826129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.233403
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