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Standardisation of oxygen exposure in the development of mouse models for bronchopulmonary dysplasia

Progress in developing new therapies for bronchopulmonary dysplasia (BPD) is sometimes complicated by the lack of a standardised animal model. Our objective was to develop a robust hyperoxia-based mouse model of BPD that recapitulated the pathological perturbations to lung structure noted in infants...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Nardiello, Claudio, Mižíková, Ivana, Silva, Diogo M., Ruiz-Camp, Jordi, Mayer, Konstantin, Vadász, István, Herold, Susanne, Seeger, Werner, Morty, Rory E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312005/
https://ncbi.nlm.nih.gov/pubmed/28067624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.027086
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