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Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of β-ENaC in a Human Alveolar Epithelial Cell Line

Acute lung injury is associated with formation of pulmonary edema leading to impaired gas exchange. Patients with acute respiratory distress syndrome (ARDS) require mechanical ventilation to improve oxygenation; however, the use of relatively low tidal volumes (to minimize further injury of the lung...

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Publicado en:Front Immunol
Autores principales: Gwoździńska, Paulina, Buchbinder, Benno A., Mayer, Konstantin, Herold, Susanne, Morty, Rory E., Seeger, Werner, Vadász, István
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440515/
https://ncbi.nlm.nih.gov/pubmed/28588583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00591
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