Immunoglobulin V(H) Gene Diversity and Somatic Hypermutation during SIV infection of Rhesus Macaques

B cell functional defects are associated with delayed neutralizing antibody development in pathogenic lentivirus infections. However, the timeframe for alterations in the antibody repertoire and somatic hypermutation (SHM) remains unclear. Here, we utilized the SIV/rhesus macaque (RM) model to inves...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Immunogenetics
Main Authors: Guo, Kejun, Halemano, Kalani, Schmitt, Kimberly, Katuwal, Miki, Wang, Yaqiong, Harper, Michael S., Heilman, Karl J., Kuwata, Takeo, Stephens, Edward B., Santiago, Mario L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439441/
https://ncbi.nlm.nih.gov/pubmed/25994147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00251-015-0844-3
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker