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Somatic immunoglobulin hypermutation

Immunoglobulin hypermutation provides the structural correlate for the affinity maturation of the antibody response. Characteristic modalities of this mechanism include a preponderance of point-mutations with prevalence of transitions over transversions, and the mutational hotspot RGYW sequence. Rec...

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Publicat a:Curr Opin Immunol
Autors principals: Diaz, Marilyn, Casali, Paolo
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621002/
https://ncbi.nlm.nih.gov/pubmed/11869898
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