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Somatic immunoglobulin hypermutation
Immunoglobulin hypermutation provides the structural correlate for the affinity maturation of the antibody response. Characteristic modalities of this mechanism include a preponderance of point-mutations with prevalence of transitions over transversions, and the mutational hotspot RGYW sequence. Rec...
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| Published in: | Curr Opin Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621002/ https://ncbi.nlm.nih.gov/pubmed/11869898 |
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