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DNA Lesions and Repair in Immunoglobulin Class Switch Recombination and Somatic Hypermutation

Immunoglobulin (Ig) gene somatic hypermutation (SHM) and class switch DNA recombination (CSR) are critical for the maturation of the antibody response. These processes endow antibodies with increased antigen-binding affinity and acquisition of new biological effector functions, thereby underlying th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Ann N Y Acad Sci
Egile Nagusiak: XU, ZHENMING, FULOP, ZSOLT, ZHONG, YUAN, EVINGER, ALBERT J., ZAN, HONG, CASALI, PAOLO
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621013/
https://ncbi.nlm.nih.gov/pubmed/16014529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1313.119
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