A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine

Current efforts to reduce the global burden of malaria are threatened by the rapid spread throughout Asia of Plasmodium falciparum resistance to artemisinin-based combination therapies, which includes increasing rates of clinical failure with dihydroartemisinin plus piperaquine (PPQ) in Cambodia. Us...

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Argitaratua izan da:mBio
Egile Nagusiak: Dhingra, Satish K., Redhi, Devasha, Combrinck, Jill M., Yeo, Tomas, Okombo, John, Henrich, Philipp P., Cowell, Annie N., Gupta, Purva, Stegman, Matthew L., Hoke, Jonathan M., Cooper, Roland A., Winzeler, Elizabeth, Mok, Sachel, Egan, Timothy J., Fidock, David A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424201/
https://ncbi.nlm.nih.gov/pubmed/28487425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00303-17
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