A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine

Current efforts to reduce the global burden of malaria are threatened by the rapid spread throughout Asia of Plasmodium falciparum resistance to artemisinin-based combination therapies, which includes increasing rates of clinical failure with dihydroartemisinin plus piperaquine (PPQ) in Cambodia. Us...

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Detaylı Bibliyografya
Yayımlandı:mBio
Asıl Yazarlar: Dhingra, Satish K., Redhi, Devasha, Combrinck, Jill M., Yeo, Tomas, Okombo, John, Henrich, Philipp P., Cowell, Annie N., Gupta, Purva, Stegman, Matthew L., Hoke, Jonathan M., Cooper, Roland A., Winzeler, Elizabeth, Mok, Sachel, Egan, Timothy J., Fidock, David A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5424201/
https://ncbi.nlm.nih.gov/pubmed/28487425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00303-17
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