Global Spread of Mutant PfCRT and Its Pleiotropic Impact on Plasmodium falciparum Multidrug Resistance and Fitness

The global spread of Plasmodium falciparum chloroquine resistance transporter (PfCRT) variant haplotypes earlier caused the widespread loss of chloroquine (CQ) efficacy. In Asia, novel PfCRT mutations that emerged on the Dd2 allelic background have recently been implicated in high-level resistance t...

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Detaylı Bibliyografya
Yayımlandı:mBio
Asıl Yazarlar: Dhingra, Satish K., Gabryszewski, Stanislaw J., Small-Saunders, Jennifer L., Yeo, Tomas, Henrich, Philipp P., Mok, Sachel, Fidock, David A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495381/
https://ncbi.nlm.nih.gov/pubmed/31040246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02731-18
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