Identification of mechanically regulated phosphorylation sites on tuberin (TSC2) that control mechanistic target of rapamycin (mTOR) signaling

Mechanistic target of rapamycin (mTOR) signaling is necessary to generate a mechanically induced increase in skeletal muscle mass, but the mechanism(s) through which mechanical stimuli regulate mTOR signaling remain poorly defined. Recent studies have suggested that Ras homologue enriched in brain (...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jacobs, Brittany L., McNally, Rachel M., Kim, Kook-Joo, Blanco, Rocky, Privett, Rachel E., You, Jae-Sung, Hornberger, Troy A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409467/
https://ncbi.nlm.nih.gov/pubmed/28289099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.777805
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