Identification of mechanically regulated phosphorylation sites on tuberin (TSC2) that control mechanistic target of rapamycin (mTOR) signaling

Mechanistic target of rapamycin (mTOR) signaling is necessary to generate a mechanically induced increase in skeletal muscle mass, but the mechanism(s) through which mechanical stimuli regulate mTOR signaling remain poorly defined. Recent studies have suggested that Ras homologue enriched in brain (...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Jacobs, Brittany L., McNally, Rachel M., Kim, Kook-Joo, Blanco, Rocky, Privett, Rachel E., You, Jae-Sung, Hornberger, Troy A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409467/
https://ncbi.nlm.nih.gov/pubmed/28289099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.777805
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