Autoregulation of the Mechanistic Target of Rapamycin (mTOR) Complex 2 Integrity Is Controlled by an ATP-dependent Mechanism

Nutrients are essential for living organisms because they fuel biological processes in cells. Cells monitor nutrient abundance and coordinate a ratio of anabolic and catabolic reactions. Mechanistic target of rapamycin (mTOR) signaling is the essential nutrient-sensing pathway that controls anabolic...

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Detalhes bibliográficos
Main Authors: Chen, Chien-Hung, Kiyan, Vladimir, Zhylkibayev, Assylbek A., Kazyken, Dubek, Bulgakova, Olga, Page, Kent E., Bersimbaev, Rakhmet I., Spooner, Eric, Sarbassov, Dos D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779703/
https://ncbi.nlm.nih.gov/pubmed/23928304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.498055
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