Identification of mechanically regulated phosphorylation sites on tuberin (TSC2) that control mechanistic target of rapamycin (mTOR) signaling

Mechanistic target of rapamycin (mTOR) signaling is necessary to generate a mechanically induced increase in skeletal muscle mass, but the mechanism(s) through which mechanical stimuli regulate mTOR signaling remain poorly defined. Recent studies have suggested that Ras homologue enriched in brain (...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Jacobs, Brittany L., McNally, Rachel M., Kim, Kook-Joo, Blanco, Rocky, Privett, Rachel E., You, Jae-Sung, Hornberger, Troy A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2017
Onderwerpen:
Signal Transduction
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409467/
https://ncbi.nlm.nih.gov/pubmed/28289099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.777805
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