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The role of raptor in the mechanical load-induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy

It is well known that an increase in mechanical loading can induce skeletal muscle hypertrophy, and a long standing model in the field indicates that mechanical loads induce hypertrophy via a mechanism that requires signaling through the mechanistic target of rapamycin complex 1 (mTORC1). Specifical...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: You, Jae-Sung, McNally, Rachel M., Jacobs, Brittany L., Privett, Rachel E., Gundermann, David M., Lin, Kuan-Hung, Steinert, Nate D., Goodman, Craig A., Hornberger, Troy A.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404572/
https://ncbi.nlm.nih.gov/pubmed/30509128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801653RR
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