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Yes-associated protein is up-regulated by mechanical overload and is sufficient to induce skeletal muscle hypertrophy
Mechanically-induced skeletal muscle growth is regulated by mTORC1. YAP is a mechanically-sensitive, and growth-related, transcriptional co-activator that can regulate mTORC1. Here we show that, in skeletal muscle, mechanical overload promotes an increase in YAP expression; however, the time course...
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| Publicado no: | FEBS Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4442043/ https://ncbi.nlm.nih.gov/pubmed/25959868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.04.047 |
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